Two NIH-funded postdoctoral research associate positions are available immediately to join the Laboratory of Molecular NeuroTherapeutics, Department of Pharmacology and Experimental Therapeutics, led by Professor Tsuneya Ikezu.
The projects attempt to characterize molecular and electrophysiological mechanisms of disease progression via extracellular vesicles (such as exosomes) in Alzheimer's disease. This is based on our recent publication (Nat Neurosci 2015, http://www.ncbi.nlm.nih.gov/pubmed/26436904), which was selected as the most impactful study in Alzheimer’s disease research in the last two calendar years (https://www.alz.org/aaic/releases_2016/awards-inge-grundke-Iqbal.asp).
The prospective members will be primarily assigned for the project exploring the cell-based functional analysis of target genes and electrophysiological characterization of mouse models using primary cultured neuronal cells with reporter genes, whole-cell path clamp, and proteomic analysis.
The laboratory is situated in Boston with rich academic research environment at the main medical campus of Boston University. Our laboratory offers excellent career opportunities at the interface of basic and translational research in collaboration with many pharmaceutical industries. Previous postdocs in our lab were awarded very prestigious fellowships from Alzheimer’s association and Bright Focus foundation, and were able to develop successful careers. The following links provide more information about the laboratory and institution: Laboratory of Molecular NeuroTherapeutics: http://www.bumc.bu.edu/busm-pm/faculty/faculty-profiles/ikezu/
Highly motivated candidates with a PhD in molecular biology or neuroscience awarded within the past three years, with strong background in molecular biology, biochemistry, primary cell cultures (i.e, iPS-derived human cells) or electrophysiology will be seriously considered. Electrophysiological part of the study will be co-directed by Professor Jennifer Luebke at the Laboratory of Cellular Neurobiology, Department of Anatomy and Neurobiology, Boston University School of Medicine (http://www.bumc.bu.edu/anatneuro/research/cellular-neurobiology/).
To inquire, please send the following files to email@example.com: Curriculum vitae (including publication list), a statement of research interest including brief description of past work, and contact information of three references.
Additional Salary Information: According to the guideline of NIH postdoctoral fellowship stipend
Dr. Ikezu’s Laboratory of Molecular NeuroTherapeutics primarily focuses on how the innate immune cells influence the central nervous system and the progression of select neurologic disorders e.g. Alzheimer’s disease and autism spectrum disorders