A 2-year postdoctoral position is available to undertake brain slice electrophysiological and calcium imaging studies of GnRH and kisspeptin neuronal phenotypes in a variety of genetic mouse models.
Experiments will involve patch-clamp electrophysiological recordings and GCaMP6 imaging associated with channelrhodopsin optogenetic manipulations in different mouse models. Studies aim to elucidate the roles of specific neural populations in regulating fertility.
The position is supported by grants awarded to Dr. Rebecca Campbell and Prof. Allan Herbison by the New Zealand Health Research Council and Marsden Fund. Recent relevant recent publications are -
1. Moore et al., Enhancement of a robust arcuate GABAergic input to GnRH neurons in a model of polycyctic ovarian syndrome. PNAS, 112, 596-601 (2015)
2. Han et al., Selective optogenetic activation of arcuate kisspeptin neurons generates pulsatile luteinizing hormone secretion. PNAS112, 13109-13114 (2015)
The position is fixed-term for two years and available immediately.
Applications closing 31st May.
Inquiries should be directed to Prof. Allan Herbison firstname.lastname@example.org
The ideal candidate will have substantial expertise in brain slice electrophysiology. Prior experience with calcium imaging and optical manipulations of neural function would be an advantage. Work will be undertaken within the University of Otago Centre for Neuroendocrinology http://www.neuroendocrinology.otago.ac.nz.