This is a job opportunity for a smart and well trained cell biologist willing to gain further qualifications in the field of synaptic transmission and disease-related pathologies in the basal ganglia. Qualified researchers are invited to apply for a research position in the Synaptic Dysfunction Lab directed by Prof. Rosemarie Grantyn at the Medical University Berlin (https://neurophysiology-grantyn.charite.de/Grantyn_page.html). The current focus of the lab is on astroglial transporters and their possible roles in corticostriatal synaptic transmission (e.g. Dvorzhak et al., 2016, J Neurosci 16:4959). To link cell-specific findings from knock-in mouse models to the motor symptoms of Huntington's and Parkinson's disease, the lab applies optogenetic tools in combination with patch clamp and imaging techniques. The experiments aim at clarifying the basis for new therapeutic strategies, including treatment with adenoviral vectors passing the blood brain barrier. The successful candidate is expected to prepare/modify the molecular/genetic tools needed to quantify the success of attempted new therapies. If necessary, the lab will provide intense personal training in optical stimulation and live imaging techniques. The position is initially granted for 24-36 months and immediately available.
Applicants with a strong background in molecular and cellular neurobiology and a recently earned PhD are particularly welcome. Previous experience in Huntington or basal ganglia research is not required but the professional expertise of the applicant must be documented in at least one 1st author publication. Interested candidates should send their inquiries or applications including a CV with photo, date and place of birth, citizenship, language skills, marital status and number of children directly to Dr. Grantyn (email@example.com).
Additional Salary Information: E13 according to the pay scale of the German Research Council