A Postdoctoral Research Associate position is available in the laboratory of Dr. Peng Jiang at the Munroe-Meyer Institute’s Developmental Neuroscience Department at the University of Nebraska Medical Center (http://unmc.edu/mmi/departments/devneuroscience/jianglab/jianglab-research.html). The research theme of the laboratory is on investigating cellular and molecular basis of neural development and pathogenesis of neurological disease utilizing human pluripotent stem cells. We focus on (i) establishing patient-derived and disease-specific human induced pluripotent stem cells (hiPSCs); (ii) creating hiPSC-based in vitro brain organoid and in vivo humanized chimeric mouse brain models to study pathogenesis of neurodevelopmental diseases, such as Down’s syndrome; and (iii) preclinical study for hiPSC-based cell therapies utilizing animal models of human CNS injuries, such as brain hypoxic-ischemic injury. We have been using a combination of multidisciplinary techniques in our research, including stem cell reprogramming, electrophysiology/patch-clamp recording, imaging techniques, molecular/cell biology (including CRISPR/cas9 technology), biochemistry, pharmacology, microarray and RNA-sequencing techniques, transgenic and surgically induced animal models, and animal behavioral testing.
Applicants should have a good publication record and a Ph.D. in physiology, neurobiology, developmental neuroscience, stem cell biology or related fields. Experience in electrophysiology/patch-clamp recording is required. Additional experience with cell culture, imaging techniques, viral preparation and infection, intracerebral cell transplantation, and animal work are desired. Candidates should also demonstrate excellent communication skills and have a strong passion and commitment to science.
To apply, please submit a CV, a cover letter stating research interests and qualifications, and references with contact information. Individuals from diverse backgrounds are encouraged to apply. All applications must be submitted to