Position Summary: A fully funded postdoctoral position is available in the laboratory of Dr. Kristin Gribble at the Marine Biological Laboratory to study the role of multi-generational mitochondrial homeostasis in neurodegenerative disease. This project takes a multidisciplinary approach, using phenotypic, transcriptomic, genetic, genomic, biochemical, and imaging methods in a novel animal model system, the monogonont rotifer.
The Gribble lab focuses on understanding the cellular, epigenetic, and evolutionary mechanisms of aging. We are specifically investigating the genetic and epigenetic mechanisms of maternal effects in determining offspring health and lifespan. For more information about the laboratory, please see http://www.mbl.edu/jbpc/gribble/.
Applicants should posses a Ph.D. and/or M.D. in molecular biology, cell biology, biochemistry, genetics, or a related field. The preferred applicant will have a background in mitochondrial biology, developmental biology, and/or neurobiology. Prior experience in confocal microscopy, RNAi, and/or bioinformatics is beneficial. The ideal candidate will have a record of scientific rigor, productivity, and creativity; the ability to work both independently and as part of a team; and a strong publication record. Excellent oral and written communication skills are required. Highly motivated individuals with experience in other model systems are encouraged to apply.
The Marine Biological Laboratory (MBL) is dedicated to scientific discovery – exploring fundamental biology, understanding biodiversity and the environment, and informing the human condition through research and education. Founded in Woods Hole, Massachusetts in 1888, the MBL is a private, nonprofit institution and an affiliate of the University of Chicago.
Research at the MBL – carried out by ...full-time MBL faculty as well as hundreds of the world’s leading scientists who are attracted by the MBL’s unique resources and strengths each year – focuses on a number of distinctive themes, including:
• new discoveries emerging from the study of novel marine organisms, encompassing research in regenerative biology, neuroscience, sensory physiology, and comparative evolution and genomics;
• the study of microbiomes and microbial diversity and ecology in a variety of ocean and terrestrial habitats;
• cutting-edge imaging and computation, making the unseen visible to illuminate cellular function and to explore biological mechanisms; and
• organismal adaptation and resilience in the face of global climate change and rapidly changing ecosystems.
The MBL has approximately 250 year-round employees, about half of which are scientists and scientific staff. These are joined each year by more than 500 scientists, summer staff, and research associates from hundreds of institutions around the world, as well as a large number of faculty and students participating in MBL courses
Among the scientists with a significant affiliation with the MBL (scientists, course faculty and students) are 57 Nobel Prize winners (since 1929); 124 Howard Hughes Medical Institute investigators, early career scientists, international researchers, and professors (since 1960); 263 Members of the National Academy of Sciences (since 1960); and 219 Members of the American Academy of Arts and Sciences (since 1960).