The Hillman lab within the Mortimer B. Zuckerman Mind Brain Behavior Institute at Columbia University develops and applies a wide range of novel optical imaging and microscopy approaches to studying the living brain. The lab is currently seeking three (3) talented post-doctoral fellows with a diverse range of expertise in the following areas:
1) Optical design - seeking an individual with optics expertise including microscopy and optical systems design, system assembly and optimization. Familiarity with light-sheet methods, scanning microscopy, optical modeling and optimization, and non-linear microscopy is desirable. Prior experience with in-vivo microscopy is an advantage, as is expertise in image and data analysis. The successful applicant will contribute to the ongoing optimization and extension of SCAPE microscopy methods for high-speed 3D imaging of brain and cellular function.
2) Brain physiology and neurovascular coupling - seeking an individual with prior in-vivo rodent brain imaging expertise and an interest in applying novel imaging methods to studying brain-wide spontaneous neural activity and its relationship to blood flow regulation in awake behaving mice. Additional expertise in fiber photometry, optogenetics and electrophysiology would be an advantage. An individual with technical training including data and image analysis is strongly preferred, although the position will have ample opportunity for learning diverse new skills.
3) Multimodal neuroimaging analysis - seeking a highly motivated individual interested in exploring novel methods of neuroimaging data analysis. This project aims to use mouse optical imaging recordings of wide-field neural activity and hemodynamics to test and inform improvements in fMRI data analysis, particularly in relation to resting state functional connectivity mapping methods. The individual may have a computational, neuroimaging or engineering background, with a preference for prior experience in fMRI analysis. The position will be jointly supervised between Columbia University PI Elizabeth Hillman and the NIMH fMRI research group directed by Peter Bandettini. Applicant could be geographically located in either New York or Washington DC areas.
Applicants are expected to be self-motivated and highly collaborative. The Hillman lab is an energetic, diverse group with broad interests spanning imaging technology development and its application to answering novel questions relating to real-time brain activity and its relation to behavior across the phylogenic spectrum. Our neurovascular coupling work seeks to better inform the interpretation of human fMRI data in health and disease through elucidation of the mechanistic underpinnings of the BOLD signal. Our group has diverse ongoing collaborations including several BRAIN initiative funded projects and a recent Simons foundation award with researchers including Rui Costa, Randy Bruno, Richard Axel, Larry Abbott, Liam Paninski, Wes Grueber and Franck Polleux.
The Hillman Lab is located within the Jerome L. Greene Science Center on Columbia's new Manhattanville campus and is part of the Mortimer B. Zuckerman Mind Brain Behavior Institute. The Zuckerman Institute brings together a large group of leading researchers to explore aspects of mind and brain, through the exchange of ideas and active collaboration. Situated in the heart of Manhattan, at full capacity the Zuckerman Institute will house approximately 58 laboratories employing a broad range of interdisciplinary approaches to transform our understanding of the mind and brain. In this highly collaborative environment, labs work together to gain critical insights into human health by exploring how the brain develops, performs, endures and recovers from trauma or disease.
Interested applicants should submit their Curriculum Vitae, cover letter, List of References, and a summary of background and research interests to Elizabeth.email@example.com.
Women and minorities are strongly encouraged to apply.
Applicants are expected to be self-motivated and highly collegial and collaborative. The Hillman lab is an energetic, diverse group with broad interests spanning imaging technology development and its application to answering novel questions relating to real-time brain activity and its relation to behavior. Our neurovascular coupling work seeks to better inform the interpretation of human fMRI data in health and disease through elucidation of the mechanistic underpinnings of the BOLD signal.
About Mortimer B. Zuckerman Mind Brain Behavior Institute at Columbia University
Located within the Jerome L. Greene Science Center in the rising Manhattanville campus of Columbia University, the Mortimer B. Zuckerman Mind Brain Behavior Institute is comprised of world-renowned scientists, bringing together psychologists, engineers, and brain scientists, with the goal of understanding the complexities of mind and brain.
The Institute supports interdisciplinary neuroscience ...research and discovery by scholars across the university and promises to be the most comprehensive institute for brain science. The Institute will also foster programming events with a focus on the community. Such programs will communicate what we currently know, and what we hope to someday know, about the brain. The intention of the Institute is to spark a scientific and creative pursuit in the next generation of scientists—and people of all ages.