UCB aspires to be the patient-centric global biopharmaceutical leader transforming the lives of people living with severe diseases. We focus on central nervous system and immunology disorders. Our promise is to help tackle the serious unmet medical needs affecting patients around the globe. An important part of our philosophy is to take a holistic approach to patients, which aims to find solutions tailored to their circumstances. By taking into account patients’ individual characteristics and lifestyles, such as age, diet, family history and genetic profile, we are also coming closer to providing personalized therapies.
With over 20 years of experience in research and development of neurology drugs, we are now building on our proven track record of innovative discovery approaches with a long-term commitment to neurology research. We now have an exciting opportunity in the New Medicines department at our research site in Belgium, close to Brussels (Braine l’Alleud), for a Research Scientist position. The candidate will join the In Vivo Pharmacology group efforts in the pharmacological characterization and development of small molecules and biologics for the treatment of neurodegenerative disorders.
Design, execute and interpret complex in vivo studies for the validation and characterization of targets or therapeutic agents in neurodegeneration.
Establish and perform in vivo model development, efficacy and pharmacokinetic/pharmacodynamic (PK/PD) biomarker studies in rodents.
May perform microsurgery studies (stereotactic injections) and in vivo activities with radioisotopes.
Manage multiple in vivo experiments simultaneously.
Analyze and present data in a clear presentation ready format.
Contribute to various projects, collaborate with stakeholders from all relevant functions, and keep up-to-date in the literature related to his/her field.
Work closely with key stakeholders across our interdisciplinary research group to prioritize and execute in vivo studies.
Participate in project teams, and demonstrate clear and professional verbal and written communication.
PhD in neuroscience, industry/ lab/ academic experience.
Knowledge of concepts of neurodegenerative mechanisms.
A solid understanding of experimental design, underlying scientific principles, and the ability to rigorously analyze and document results.
Experience with small laboratory animal: pharmacological agent administration via IV, IP, SC, IM and PO dosing routes; handling and surgery; tissue harvest and biochemical fractionation methods. Experience in micro-dissection is a plus.
Thorough experience with data analysis software.
Strong interpersonal and organizational skills, ability to clearly communicate results and to maintain detailed written records.
Ability to effectively present scientific data and concepts to colleagues and teams is required, and experience presenting at external meetings is desirable.
Experience in writing technical drafts for ethical committee and HSE.
Working fluency in English
Accreditation or Certification of Regularization by Federation of European Laboratory Animal Science Associations (FELASA), or similar foreign certification.