The Laboratory of Addictive Disorders is located in the Department of Pharmacology and Experimental Therapeutics on the Boston University Medical Campus. Our research is aimed at understanding the neurobiological substrates of alcohol and drug addiction, anxiety and stress-related disorders, food intake and eating disorders, impulsivity. Studies are carried out on environmental and genetic rodent models, using a multidisciplinary behavioral, pharmacological, biochemical, and molecular approach. Techniques currently used in the laboratory are: self-administration (food, alcohol, ICSS), intracranial surgeries (for implantation of electrodes/cannulas or for viral vector microinfusion), place conditioning, anxiety and depression tests (elevated plus-maze, light-dark box test, defensive withdrawal, forced swim test, tail suspension test, novelty suppression of feeding), alcohol dependence induced by vapor exposure, real-time PCR, immunohistochemistry, western blotting, GTPgammaS, DREADDs, and viral vector technology to study site-specific gene knockdown in the brain.
Animal models are used as the basis for all experiments; therefore, those with a strong background in behavioral neuroscience are encouraged to apply. Applicants who consider themselves independent, intensely motivated to succeed, and hard-working are encouraged to apply.
The PIs will be happy to interview in person on 11-11-2017 and 11-12-2017 the candidates who are planning to attend the SfN meeting in Washington DC.
A leader in medical education and research, Boston University School of Medicine (BUSM) provides an exceptional environment for students interested in basic science, clinical investigation, or public health- and health services-oriented research.