A postdoctoral associate position is available immediately in the Jacob lab (Pharmacology & Chemical Biology Department 1, University of Pittsburgh School of Medicine and member of Center for Neuroscience2). The Jacob lab’s broad goal is to uncover molecular signaling mechanisms and understand the impact of dynamically regulated GABAA receptor (GABAAR) surface levels and distribution in normal development, pathological conditions, and during drug therapy. The lab uses in vitro and in vivo models, applying high-resolution live imaging, pharmacological, molecular, biochemical, and electrophysiological approaches.
We are seeking a postdoc to contribute to ongoing investigations focused on molecular mechanisms underlying tolerance to benzodiazepines, a critical drug class that positively modulates GABAARs and are used as front-line treatments for anxiety, insomnia, schizophrenia and epilepsy. This work relies on a multidisciplinary approach using biochemistry, electrophysiology, imaging, and behavior.
Candidates will have recently obtained a Ph.D (within the last two years) and have a strong background in neuroscience, pharmacology, biochemistry or molecular and cell biology. Candidates should also have a first author paper published or accepted in a well recognized peer-reviewed journal. Preference will be given to individuals with experience in biochemistry, high resolution microscopy, or electrophysiology.
Strong self-motivation, independence and good communication skills to work in a collaborative environment!
Interested candidates should send a letter of interest (including a brief description of research interests and career goals), CV and contact information for three references to Dr. Tija Jacob, Ph.D. (email@example.com).