The Heller Lab is seeking a Research Specialist, with lab management responsibilities.
The Heller Lab studies the mechanisms by which remodeling of the epigenome leads to aberrant neuronal gene function and behavior. To approach this problem, we directly manipulate histone and DNA modifications at specific genes in mouse brain, using viral delivery of novel epigenetic editing tools. We focus on uncovering the mechanisms by which chromatin modifications interact with the transcriptional machinery following exposure to psychostimulants, such as drugs of abuse and stress.
Responsibilities include lab supply and animal ordering, chemical maintenance, waste disposal, and equipment maintenance (including surgical isoflurane system, fluorescent stereoscope, freezers).
In addition, this position involves management of a mouse breeding colony, with the assistance of a work-study student.
Depending on the experience and interests of the trainee, research activities may additionally include mouse brain dissection, isolation of nucleic acid, PCR, chromatin-immunoprecipitation, cell culture and transfections, mouse intracranial stereotaxic surgery, drug self-administration behavior, subchronic variable stress behavior, and more.
All members of the Hellerlab participate in the ongoing research and receive mentorship and training from Dr. Heller and other members of the group.
Please see the website for more information: http://www.med.upenn.edu/hellerlab/
Applicants should have a BA or BS in a related area and prior wet lab research experience.
Animals with experience in rodent laboratory research will be prioritized.
Start date of June 1, 2018.
Minimum two year commitment.
US Citizen or Green Card Holder.
Additional Salary Information: Salary is determined by the Perelman School of Medicine commensurate with experience and includes an automatic 3% annual increase. Annual reappointment is required.
About The University of Pennsylvania, Perelman School of Medicine
The University of Pennsylvania is the oldest and one of the finest medical schools in the United States. Penn is rich in tradition and heritage and at the same time consistently at the forefront of new developments and innovations in medical education and research. Since its founding in 1765 the School has been a strong presence in the community and prides itself on educating the leaders of tomorr...ow in patient care, biomedical research, and medical education.
At Penn academic excellence, as well as compassion for the patients we are privileged to serve, are stressed. Skillful compassion is truly a hallmark of the Penn learning experience. The Perelman School of Medicine at the University of Pennsylvania consistently ranks among the top five in US News and World Report’s rankings of research-oriented medical schools.