The brain has an active response to injury and disease, with neuronal and glial progenitor responses that lead to partial repair and recovery. This neural repair in the brain occurs in specialized cellular niches, where these progenitors develop in close approximation: angiogenesis, neurogenesis and gliogenesis appear to be coordinately regulated in diseases such as stroke and Alzheimer’s disease in tissue that is adjacent to the sites of injury or damage. The biology behind this process of tissue repair is not well defined. There are two post-doctoral fellowships opening in an exciting new project to utilize systems biology to identify the molecular and cellular signaling systems in this neurovascular niche for tissue repair in the brain. These studies will utilize advanced approaches for cell-specific isolation and RNAseq and bioinformatic analyses. The research occurs within three highly collaborative laboratories at UCLA, and an environment that is expert in molecular and cellular studies of neural repair and of computational analysis of transcriptome data sets. The post-doctoral positions are in separate projects, stroke and neurodegenerative disease, so that each post-doc has distinct activities and resultant papers.
UCLA is an interesting and dynamic place for neuroscience study and for a post-doctoral fellowship. The neuroscience community is rich with symposia, seminars and collaborators that offer deep exposure to cutting edge techniques, emerging ideas and scientific pathways forward. Los Angeles is a diverse city with plenty of sunshine and beaches, easy access to skiing and excellent mountain biking and backpacking. Excellent science, sunshine and the Great Outdoors!
Previous experience in molecular, cellular or systems biology studies.