A position for a highly motivated postdoctoral associate is available in the laboratory of Dr. Yang Yang, Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University.
The project will involve the study of ion channel dysfunctions related epilepsy, autism or chronic pain, using whole animal behavior tests (including EEG recording), dissociated cells and brain slice patch-clamp recordings, and functional studies of neurons differentiated from induced Pluripotent Stem Cells (iPSCs) (Nat Commun 2012, Nat Rev Neurosci 2013, J Neurosci 2016).
For applicants who are resident in China, positions will be available via a joint program between Dr. Yang Yang’s lab at Purdue University and Dr. Zhuo Huang’ lab at Peking University. For this joint program, the initial appointment will be at Peking University with full benefits, highly competitive salary, school-provided housing, guaranteed Beijing household Register (Hukou), health insurance, among others. After successful enrollment, the applicant will be expected to join Purdue University to further continue the study.
The successful applicant should have completed a PhD in neuroscience or a related field (within two years) and should have experience with animal surgery, animal behavior experiments (e.g. EEG recording) related to epilepsy/autism, or experience with patch-clamp electrophysiology. To apply, please send a current C.V. and statement of research interests to Dr. Yang Yang (email@example.com).
Purdue University ranks No. 4 Public University in the U.S. by Wall Street Journal/Times Higher Education. And Purdue College of Pharmacy ranks No. 9 among all pharmacy programs in the U.S. by US News Eductation.
More information about Dr. Yang Yang and Dr. Zhuo Huang’s research can be found in the following webpages:
The focus of the research in Y-lab is on channelopathies of the nervous system. Channelopathies are diseases related to the dysfunction of ion channels, which are pore-forming membrane proteins that allow ions to pass through the cell membrane, controlling many indispensable functions of cells, including the generation of action potentials in neurons. Channelopathies, often resulting from inherite...d or de novo mutations, are responsible for a variety of human neurological diseases including chronic pain, epilepsy and autism.
Using state-of-the-art technologies (structural modeling, patch-clamp recordings, multi-electrode array recordings, live cell imaging, induced pluripotent stem cells, CRISPR-mediated genome-editing, and transgenic rodent models), Y-lab aims to understand how dysfunctions of ion channels contribute to neurological diseases, and to develop novel pharmacogenomic approaches targeting ion channels for disease intervention.